Imcyse, who develop active specific immunotherapies for the treatment and prevention of severe chronic diseases, today announces the successful enrolment of 41 patients with recent-onset type 1 diabetes into its first-in-human Phase 1b study.
The double-blind, placebo-controlled, dose-escalation clinical study recruited patients with insulin-dependent type 1 diabetes diagnosed within six months prior to inclusion, from seven European countries (Belgium, Denmark, France, Germany, Lithuania, Sweden and the UK). The trial investigates the safety, the immunological responses and the clinical impact of Imcyse’s unique Imotopes™ technology. An independent data safety monitoring committee review has rated the safety profile so far as excellent. Complete results are expected in summer 2019.