Committed to transforming
the treatment of severe, chronic
autoimmune diseases.

Committed to transforming
the treatment of severe, chronic
autoimmune diseases.

Ref : IDT-RA


Permanent contract

About Imcyse

Imcyse is a clinical-stage biotech company pioneering the development of a new class of active, specific immunotherapeutics known as ImotopesTM. Imcyse’s innovative technology platform is based on the discovery of modified synthetic peptides that induce specific CD4 T-cells able to eliminate the pathogenic immune cells causing autoimmune diseases. Imcyse’s ImotopesTM hold the promise to cure patients suffering from severe chronic autoimmune diseases for which there is no adequate therapeutic alternative. Currently, a phase 2 clinical study is ongoing in type-1 diabetes and we are reaching completion of pre-clinical development in multiple sclerosis while projects in several other autoimmune diseases are at an earlier stage of development. We are a highly dynamic world-class team dedicated to utilizing our unique ImotopeTM technology platform to improve the lives of patients suffering from these debilitating diseases.

For its development Imcyse is looking for a:




  • Is in charge of LC-MS quality control of external peptides or peptides produced internaly
  • Is responsible for running solubility, binding, thioredox and adsorption assays on peptides.
  • Is responsible for running stability studies (ICH Q1A, Q1B, Q1C, Q1D, Q1E, Q1F)
  • Performs laboratory experiments following the protocols and SOP’s.
  • Records the data on the appropriate media (lab book, study reports, company’s server) in line with company policies.
  • Is accountable for generated results.
  • Is responsible for the reporting of results in adequate format (ppt, development report) to the Head of IDT & CMC and to Project Team
  • Takes part of the development, internalization, qualification or validation of analytical assays (ICH Q2; USP 1244, 1255, 1256).
  • Is responsible for running internal peptide manufacturing (synthesis, purification, freeze-drying).
  • Anticipates the company’s needs and takes part of the constant search for new equipment, methods, and solutions.
  • Maintains the safe and clean working environment.
  • Reports to the Head of IDT and CMC.


  • Bachelor’s degree in Chemistry, Biochemistry or Medical Biology with a minimum of 3 years of experience or Master’s degree in Chemistry, Biochemistry or Medical Biology with a minimum of 1 year of experience
  • Working experience in Quality Control (QC) laboratory or Analytical Development department
  • Working experience in (U)HPLC-MS.
  • Strong affinity towards analytical sciences and willingness to learn.
  • French and English verbal and written communication skills are required.
  • Must be able to work in autonomy, respond to changing priorities and short lead times for multiple tasks; able to identify problems and work towards solutions


This position contributes to and supports the company’s research and development efforts to create high value therapeutics to address unmet medical needs.
We offer a permanent position in an innovating and dynamic company located near Liège and an attractive salary package in line with the position responsibilities and your experience.


Please send your CV together with a cover letter to the following address: Please, mention the following reference: 2022/IDT-RA.
Your application and related information will remain strictly confidential and will be used in the strict context of this recruitment, in line with GDPR.

©imcyse 2023